The first experience of using the adaptive phage therapy technique in chronically critically ill patients in neurological intensive care demonstrated the safety of inhalational administration of the bacteriophage cocktail.
The efficacy of the technique was confirmed by the treatment results obtained in the phage therapy group, which were not inferior to those in the group with conventional antibiotic therapy, while several clinical and laboratory parameters tended to improve even in patients who received bacteriophages and did not receive antibiotics.
The results of our study are presented in an article for the
General Reanimatology Journal.
The authors of the article are N.V. Beloborodova, A.V. Grechko, M.M. Gurkova, A.Yu. Zurabov, F.M. Zurabov, A.N. Kuzovlev, A.Yu. Meglei, M.V. Petrova, V.M. Popova, I.V. Redkin, N.I. Sergeev, E.A. Chernevskaya, M.Yu. Yuriev, A.A. Yakovlev.